发明申请
- 专利标题： Dihydropyrimidines and uses thereof
- 专利标题（中）： 二氢嘧啶及其用途
-
申请号： US10702579申请日： 2003-11-06
-
公开(公告)号： US20040138242A1公开(公告)日： 2004-07-15
- 发明人: Donghui Cui , Margaret R. Davis , Michael Dunn , Ben E. Evans , Hanumath P. Kari , Bharat Lagu , Dhanapalan Nagarathnam , Kamlesh P. Vyas , Kanyin Zhang
- 申请人： Merck and Co., Inc. , Synaptic Pharmaceutical Corporation
- 申请人地址： null null
- 专利权人： Merck and Co., Inc.,Synaptic Pharmaceutical Corporation
- 当前专利权人： Merck and Co., Inc.,Synaptic Pharmaceutical Corporation
- 当前专利权人地址： null null
- 主分类号： A61K031/513
- IPC分类号： A61K031/513 ; C07D239/02
摘要：
This invention is directed to dihydropyrimidines which are selective antagonists for human null1a receptors. This invention is also related to uses of these compounds for relaxing lower urinary tract tissue, treating benign prostatic hyperplasia and for the treatment of any disease where the antagonism of the null1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
信息查询
