发明申请
US20040053957A1 Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
有权
取代的3-氨基 - 噻吩并[2,3-b]吡啶-2-羧酸酰胺化合物及其制备方法及其用途
![Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses](/docs/US/2004-03-18/US20040053957A1/abs.jpg.600x600.jpg)
- 专利标题： Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
- 专利标题（中）： 取代的3-氨基 - 噻吩并[2,3-b]吡啶-2-羧酸酰胺化合物及其制备方法及其用途
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申请号： US10453175申请日： 2003-06-03
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公开(公告)号： US20040053957A1公开(公告)日： 2004-03-18
- 发明人: Charles L. Cywin , Zhidong Chen , Roman Wolfgang Fleck , Ming-Hong Hao , Eugene Hickey , Weimin Liu , Daniel Richard Marshall , Peter Nemoto , Ronald John Sorcek , Sanxing Sun , Jiang-Ping Wu , Tina Morwick , Jonathan Emeigh
- 申请人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 申请人地址： US CT Ridgefield
- 专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址： US CT Ridgefield
- 主分类号： C07D498/02
- IPC分类号： C07D498/02 ; A61K031/4743
![Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses](/abs-image/US/2004/03/18/US20040053957A1/abs.jpg.150x150.jpg)
摘要：
Disclosed are compounds of formula (I): 1 wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the InullB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
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