发明申请
US20020165355A1 Methylated, SmD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus
审中-公开
甲基化，SmD同源肽与受系统性红斑狼疮影响的生物血清的抗体反应
- 专利标题： Methylated, SmD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus
- 专利标题（中）： 甲基化，SmD同源肽与受系统性红斑狼疮影响的生物血清的抗体反应
-
申请号： US10056407申请日： 2002-01-24
-
公开(公告)号： US20020165355A1公开(公告)日： 2002-11-07
- 发明人: Lydie Meheus , Reinhard Georg Luhrmann , Ann Union , Joseph Raymackers
- 申请人： INNOGENETICS N.V.
- 申请人地址： null
- 专利权人： INNOGENETICS N.V.
- 当前专利权人： INNOGENETICS N.V.
- 当前专利权人地址： null
- 优先权： EP97870127.4 19970829
- 主分类号： C07K001/00
- IPC分类号： C07K001/00 ; C07K014/00 ; C07K017/00
摘要：
The present invention relates to a method of producing certain peptides containing methylated arginines that are followed by a glycine residue and that constitute immunogenic determinants of antibodies present in sera from patients with systemic lupus erythematosus, or Epstein-Barr virus and wherein the methylation is a prerequisite for reacting with said antibodies. The invention also relates to the use of said peptides for diagnosis and treatment of systemic lupus erythematosus and related diseases, and diseases in which Epstein-Barr virus has been implicated.
信息查询
