A prefabricated concrete panel for industrialized building, with high thermal and/or acoustic insulation, comprising a first sheet and a second sheet which are embedded in the concrete body of the panel and face each other on planes which are parallel to the planes of arrangement of the two larger faces of the panel. At least one of the sheets is made of thermally insulating material and the sheets delimit, therebetween, an air chamber which is divided into a plurality of mutually connected recesses in order to increase thermal and/or acoustic insulation of the panel.