The present disclosure relates to the technical field of display screen, and provides a display module set and a display screen. The display module set comprises a cabinet frame and a plurality of display modules. The cabinet frame comprises a power box and a plurality of sub-frames located on the left and right sides of the power box. The sub-frames on each side are arranged sequentially in a vertical direction. The plurality of the display modules corresponds to a plurality of the sub-frames on a one-to-one basis. A drive circuit and mounting members of the display module are both provided on a left side and/or right side region. A middle region of the display module is uniformly distributed with a hole structure for sound transmission. The display module is mounted on a corresponding sub-frame via the mounting members of the left side and/or right side region.