Invention Grant
- Patent Title: Methods for identifying and modulating co-occurant cellular phenotypes
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Application No.: US16494911Application Date: 2018-03-19
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Publication No.: US12180546B2Publication Date: 2024-12-31
- Inventor: Alexander K. Shalek , Alexander S. Genshaft , Carly G. K. Ziegler , Jeffrey F. Van Humbeck , Ryan Philip King
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Johnson, Marcou, Isaacs & Nix, LLC
- Agent F. Brent Nix, Esq.; Drew P. Harding
- International Application: PCT/US2018/023170 WO 20180319
- International Announcement: WO2018/170515 WO 20180920
- Main IPC: C12Q1/6881
- IPC: C12Q1/6881 ; C07D405/12 ; C07D495/04 ; C12Q1/6869 ; G01N1/28 ; G16B45/00
Abstract:
The present invention provides tools and methods for the systematic analysis of genetic interactions between cells. The present invention provides tools and methods for modulating cell phenotypes and compositions, combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.
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