Invention Grant
- Patent Title: Stable, concentrated radionuclide complex solutions
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Application No.: US18640907Application Date: 2024-04-19
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Publication No.: US12161732B2Publication Date: 2024-12-10
- Inventor: Donato Barbato , Clementina Brambati , Daniela Chicco , Francesco de Palo , Lorenza Fugazza , Maurizio Mariani , Giovanni Tesoriere
- Applicant: Advanced Accelerator Applications SA
- Applicant Address: FR Rueil-Malmaison
- Assignee: Advanced Accelerator Applications SA
- Current Assignee: Advanced Accelerator Applications SA
- Current Assignee Address: FR Rueil-Malmaison
- Agent Derek Denhart; Lian Ouyang
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61K33/24 ; A61K51/04 ; A61M36/14 ; C22B59/00

Abstract:
The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.
Public/Granted literature
- US20240285813A1 Stable, concentrated radionuclide complex solutions Public/Granted day:2024-08-29
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