- 专利标题: Method for producing an antitumoral arenavirus as well as arenavirus mutants
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申请号: US17275967申请日: 2019-09-12
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公开(公告)号: US12129281B2公开(公告)日: 2024-10-29
- 发明人: Karl Lang , Cornelia Hardt , Michael Bergerhausen , Hilal Bhat
- 申请人: ABALOS THERAPEUTICS GMBH
- 申请人地址: DE Dusseldorf
- 专利权人: ABALOS THERAPEUTICS GMBH
- 当前专利权人: ABALOS THERAPEUTICS GMBH
- 当前专利权人地址: DE Dusseldorf
- 代理商 Michael A. Whittaker
- 优先权: DE 2018215551.8 2018.09.12
- 国际申请: PCT/EP2019/074307 2019.09.12
- 国际公布: WO2020/053324A 2020.03.19
- 进入国家日期: 2021-03-12
- 主分类号: C07K14/08
- IPC分类号: C07K14/08 ; A61K35/76 ; A61K35/768 ; A61K45/06 ; A61P35/00 ; C07K14/005 ; C12N7/00
摘要:
The invention relates to a mutant of an arenavirus having improved antitumoral properties. The invention also relates to a method of generating such an arenavirus mutant, related pharmaceutical compositions, medical uses, methods of treatment, and isolated proteins and nucleic acids.
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