Invention Grant
- Patent Title: Substituted indoles and methods of use thereof
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Application No.: US17268151Application Date: 2019-08-14
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Publication No.: US12116358B2Publication Date: 2024-10-15
- Inventor: John Lampe , John Campbell , Kenneth Duncan , Megan Alene Cloonan Foley , Darren Martin Harvey , Michael John Munchhof , Michael Thomenius , Lawrence Alan Reiter
- Applicant: EPIZYME, INC.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Dechert LLP
- Agent Danielle M. Paglia; Erica M. D'Amato
- International Application: PCT/US2019/046569 2019.08.14
- International Announcement: WO2020/037079A 2020.02.20
- Date entered country: 2021-02-12
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61P35/00 ; C07D209/42 ; C07D209/96 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/14 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D471/08 ; C07D471/10 ; C07D487/04 ; C07D487/08 ; C07D487/10 ; C07D491/08 ; C07D491/107 ; C07D498/04 ; C07D498/08 ; C07D498/10 ; C07D513/10
Abstract:
Compounds of Formula I: (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1e, G1, G2, Q1, Q2, Q3, and (II) are defined as set forth in the specification, as are uses of compounds of Formula I to treat a disease, disorder, or condition such as cancer in a subject.
Public/Granted literature
- US20230075198A1 SUBSTITUTED INDOLES AND METHODS OF USE THEREOF Public/Granted day:2023-03-09
Information query
