The present invention relates to a technology related to an exfoliative cell processing device which obtains exfoliative cells out of a vial which has contained specimen of exfoliative cells (e.g., exfoliative cells and liquid medium) of a human body and then thinly smears the exfoliative cells on a cell smear slide. More specifically, the present invention relates to a technology for vertically entering the upper entrance of a vial which containing a specimen so as to extract a part of the specimen from the vial and then for thinly smearing the part of specimen on a cell smear slide which being disposed adjacent to the vial. The present invention has an advantage in that exfoliative cells may be attached in a thinly spread state on the lower surface of the specimen collector since the process of suctioning specimen from the vial.