• 专利标题: Biocompatible hydrogel, process for producing same, and use thereof in a mechanical viscosupplementation system
  • 申请号: US17298349
    申请日: 2019-12-02
  • 公开(公告)号: US12102735B2
    公开(公告)日: 2024-10-01
  • 发明人: Jean-Claude GiannottaCharles Calleja
  • 申请人: NVD
  • 申请人地址: FR Biot
  • 专利权人: NVD
  • 当前专利权人: NVD
  • 当前专利权人地址: FR Biot
  • 代理机构: Seckel IP, PLLC
  • 优先权: FR 72196 2018.11.30
  • 国际申请: PCT/EP2019/083356 2019.12.02
  • 国际公布: WO2020/109628A 2020.06.04
  • 进入国家日期: 2021-05-28
  • 主分类号: A61L27/16
  • IPC分类号: A61L27/16 A61L27/18 A61L27/20 A61L27/52 A61L27/54 A61L27/58 C08L33/26
Biocompatible hydrogel, process for producing same, and use thereof in a mechanical viscosupplementation system
摘要:
A biocompatible hydrogel has between 0.3% and 30% by weight of dry matter of a copolymer formed at least from acrylamide, chitosan and N,N′-methylenebisacrylamide, as well as a diffusing agent. The diffusing agent is advantageously selected from the group consisting of inert ingredients which have biomechanical properties and active ingredients. A method of manufacturing the hydrogel by copolymerizing, washing, and adding the diffusing agent is provided, as well as a mechanical visco-supplementation system adapted for external or internal use that includes the hydrogel, and an external or internal mechanical visco-supplementation kit including an acrylamide and chitosan copolymer crosslinked with N,N′-methylenebisacrylamide, and a diffusing agent in solid phase or in suspension, the copolymer and the diffusing agent having been previously mixed in the form of a hydrogel during manufacture or being adapted to be mixed extemporaneously to form a hydrogel.
信息查询
0/0