In one example, a method includes instructing a mobile device of a user to establish a connection with an application server via a first network slice, where the first network slice is configured based on an initial resource need of a network connected application executing on the mobile device and an initial set of network conditions, sending, to the mobile device, a prediction of at least one network condition for the first network slice at a time in the future, receiving, from the mobile device, an indication of an updated resource need of the network connected application, and providing, to the mobile device, instructions for establishing a connection to the application server over a second network slice, where the second network slice is configured based on the updated resource need and a current set of network conditions.