Systems and methods are provided that support configuration of settings of an Information Handling System (IHS), such as by external configuration tools that are delegated authority to configure any portion of the configurable settings of IHS. During factory provisioning of the IHS, an inventory of configurable settings of the IHS is generated and permissions are assigned for configuration of a portion of the configurable IHS settings by a configuration tool. During the factory provisioning, credentials are stored to the IHS for authenticating communications from the assigned configuration tool. Once the IHS has been delivered and deployed, configuration of the assigned portion of IHS is allowed when configuration requests from the assigned configuration tool are successfully validated against the credentials stored to the IHS during factory provisioning. The configurable settings of the IHS may include BIOS settings, operating system settings and settings supported by hardware components of the IHS.