Invention Grant
- Patent Title: Anti-CXCR5 antibodies and compositions and uses thereof
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Application No.: US17100245Application Date: 2020-11-20
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Publication No.: US11958901B2Publication Date: 2024-04-16
- Inventor: Rachel Groth , William Brian Snyder , Xianjun Cao , Robert Joseph Dunn , Joseph Dal Porto , Michael Karin
- Applicant: PFIZER INC. , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.,The Regents of the University of California
- Current Assignee: Pfizer Inc.,The Regents of the University of California
- Current Assignee Address: US NY New York; US CA Oakland
- Agency: Wolf, Greenfield & Sacks, P.C.
- The original application number of the division: US16202749 2018.11.28
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00 ; A61P19/02 ; A61P37/06 ; C07K16/24 ; C07K16/40 ; C12N15/62
Abstract:
The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.
Public/Granted literature
- US20210101970A1 ANTI-CXCR5 ANTIBODIES AND COMPOSITIONS AND USES THEREOF Public/Granted day:2021-04-08
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