Invention Grant
- Patent Title: Modulators of HSD17B13 and methods of use thereof
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Application No.: US17622454Application Date: 2020-07-01
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Publication No.: US11957687B2Publication Date: 2024-04-16
- Inventor: Joseph Vacca
- Applicant: REGENERON PHARMACEUTICALS, INC.
- Applicant Address: US NY Tarrytown
- Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee Address: US NY Tarrytown
- Agency: Troutman Pepper Hamilton Sanders LLP
- International Application: PCT/US2020/040542 2020.07.01
- International Announcement: WO2021/003295A 2021.01.07
- Date entered country: 2021-12-23
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/4412 ; A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/4436 ; A61K31/4439 ; A61K31/444 ; A61K31/4545 ; A61K31/4709 ; A61K31/4725 ; A61K31/496 ; A61K31/497 ; A61K31/506 ; A61K31/513 ; A61P1/16 ; C07D213/82 ; C07D239/36 ; C07D239/56 ; C07D295/135 ; C07D401/12 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D498/04 ; C07D513/04
Abstract:
The disclosure relates to compounds and pharmaceutical compositions capable of modulating the hydroxysteroid 17-beta dehydrogenase (HSD17B) family member proteins including inhibiting the HSD17B member proteins, e.g. HSD17B13. The disclosure further relates to methods of treating liver diseases, disorders, or conditions with the compounds and pharmaceutical compositions disclosed herein, in which the HSD17B family member protein plays a role.
Public/Granted literature
- US20230094341A1 MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF Public/Granted day:2023-03-30
Information query
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