- 专利标题： Replication-enhanced oncolytic adenoviruses
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申请号： US17091549申请日： 2020-11-06
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公开(公告)号： US11951141B2公开(公告)日： 2024-04-09
- 发明人: Mark J. Cantwell , Amer A. Beg
- 申请人： MEMGEN, Inc. , H. Lee Moffitt Cancer Center and Research Institute, Inc.
- 申请人地址： US TX Houston
- 专利权人： MEMGEN, INC.,H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- 当前专利权人： MEMGEN, INC.,H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- 当前专利权人地址： US TX Houston; US FL Tampa
- 代理机构： Jackson Walker LLP
- 代理商 Leisa Talbert Peschel
- 主分类号： A61K35/761
- IPC分类号： A61K35/761 ; A61P35/00 ; C12N7/00 ; C12N15/113 ; C12N15/12 ; C12N15/22
摘要：
Disclosed are replication-enhanced oncolytic adenoviruses. These oncolytic adenoviruses have tumor-specific replication capable of enhanced tumor oncolysis and enhanced therapeutic transgene expression. Also disclosed are methods comprising administering a replication-enhanced oncolytic adenovirus for patients suffering from a cancer.
公开/授权文献
- US20210128653A1 REPLICATION-ENHANCED ONCOLYTIC ADENOVIRUSES 公开/授权日：2021-05-06
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