Technologies are provided for classifying detected events as labeled event combinations. Input data for different combinations of detected events are received at a server system, and each combination of detected events is processed at the server system. Processing can include classifying that combination of detected events at a classifier to map that combination of detected events to a probability of an increased insulin delivery demand or a probability of a decreased insulin delivery demand, and labeling each classified combination of detected events with a label to generate a corresponding labeled event combination that has the probability of the increased insulin delivery demand or the probability of the decreased insulin delivery demand. Each labeled event combination can be stored in storage as a database of labeled event combinations, and selected ones of the labeled event combinations can be processed at a client application to generate an output result.