Systems and methods are disclosed comprising a data transfer and search facility adapted to access content, such as variables and cases, stored on a plurality of disparate computer content storage facilities. The variable data may comprise scientific data. The access of variables may be performed over an encrypted network. A user filter specification may be received and corresponding variables or cases may be identified using a search engine, the user may select which of the identified variables are to be transferred, and the variable data may be transferred from a source storage facility to a destination file. Missing variables values may be identified and a determination is made whether the identified number of missing variables values exceeds a threshold. Encoding of variable data is performed. The variable data may be provided to one or more statistical data analysis and processing applications.