Invention Grant
- Patent Title: Method and system for treating cancer
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Application No.: US17025269Application Date: 2020-09-18
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Publication No.: US11826353B2Publication Date: 2023-11-28
- Inventor: Tomer Shlomi , Won Dong Lee
- Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
- Applicant Address: IL Haifa
- Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
- Current Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
- Current Assignee Address: IL Haifa
- Agency: BROWDY AND NEIMARK, PLLC
- Main IPC: A61K31/4162
- IPC: A61K31/4162 ; A61P35/00 ; G01N33/574
Abstract:
The invention provides a method for treating cancer in which a level of reduced folate carrier (RFC) or folylpolyglutamate synthetase (FPGS) in cancer cells of the biopsy is determined. If the level of RFC or FPGS in the cancer cells is below a threshold value, the cancer is treated with an inhibitor of serine-hydroxymethyl-transferase (SHMT)1. If the level of RFC or FPGS in the cancer cells is above the threshold value, the cancer is treated with an inhibitor of SHMT2.
Public/Granted literature
- US20210077462A1 METHOD AND SYSTEM FOR TREATING CANCER Public/Granted day:2021-03-18
Information query
IPC分类:
