Invention Grant
- Patent Title: MCT4 inhibitors for treating disease
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Application No.: US17481660Application Date: 2021-09-22
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Publication No.: US11724989B2Publication Date: 2023-08-15
- Inventor: Kenneth Mark Parnell , John McCall
- Applicant: Vettore, LLC
- Applicant Address: US CA San Francisco
- Assignee: Vettore, LLC
- Current Assignee: Vettore, LLC
- Current Assignee Address: US CA San Francisco
- Agent Cynthia Hathaway; Lauren L. Stevens; Erik M. Larsen
- The original application number of the division: US15180623 2016.06.13
- Main IPC: C07D231/12
- IPC: C07D231/12 ; A61P35/00 ; A61K31/415 ; A61K31/4155 ; A61K31/427 ; A61K31/4439 ; A61K31/5377 ; A61K45/06 ; C07D401/06 ; C07D405/12 ; C07D409/04 ; C07D417/04
Abstract:
Provided herein is a method for treating a monocarboxylate transporter MCT4-mediated disorder in a subject in need thereof. The method comprises the step of administering to the subject a compound of structural Formula I
and/or a salt thereof. The treatment of the monocarboxylate transporter MCT4-mediated disorder may inhibit activity of MCT4, or a mutant thereof, sometimes with at least a 100-fold selectivity for MCT4 over MCT1.
and/or a salt thereof. The treatment of the monocarboxylate transporter MCT4-mediated disorder may inhibit activity of MCT4, or a mutant thereof, sometimes with at least a 100-fold selectivity for MCT4 over MCT1.
Public/Granted literature
- US20220251045A1 MCT4 INHIBITORS FOR TREATING DISEASE Public/Granted day:2022-08-11
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