- 专利标题： N-acyl amino acid compounds and methods of use
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申请号： US16809244申请日： 2020-03-04
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公开(公告)号： US11673887B2公开(公告)日： 2023-06-13
- 发明人: Lan Jiang , David John Morgans, Jr. , Gustave Bergnes , Chun Chen , Hui Li , Patrick Andre , Randall Halcomb , Jacob Cha , Timothy Hom
- 申请人： Pliant Therapeutics, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Pliant Therapeutics, Inc.
- 当前专利权人： Pliant Therapeutics, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Morrison & Foerster LLP
- 代理商 Kraig Anderson, Pliant; Johannes Hull, Pliant
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D213/74 ; C07D233/70 ; C07D233/88 ; C07D241/06 ; C07D241/08 ; C07D263/28 ; C07D265/08 ; C07D277/18 ; C07D279/06 ; C07D498/04 ; A61P1/00 ; A61P1/16 ; A61P9/00 ; A61P11/00 ; A61P13/12 ; A61P17/00
摘要：
The invention relates to compounds of formula (I):
or a salt thereof, wherein R1, A, L, and R2 and n are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are αvβ1 integrin inhibitors that are useful for treating tissue specific fibrosis.
or a salt thereof, wherein R1, A, L, and R2 and n are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are αvβ1 integrin inhibitors that are useful for treating tissue specific fibrosis.
公开/授权文献
- US20210024516A1 N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE 公开/授权日：2021-01-28
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