Invention Grant
- Patent Title: Substituted pyrimidines and methods of use
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Application No.: US17301242Application Date: 2021-03-30
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Publication No.: US11673879B2Publication Date: 2023-06-13
- Inventor: Mandy Loo , Svitlana Kulyk , Christopher Bailey , Jennifer Kozak , Matthew B. Soellner , Adam D. Hughes
- Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
- Applicant Address: US CA South San Francisco
- Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee Address: US CA South San Francisco
- Agency: Sheppard Mullin Richter & Hampton LLP
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/506 ; A61K9/12 ; A61P1/16 ; A61P9/00 ; A61P11/00 ; A61P35/00 ; A61K9/00 ; A61K45/06

Abstract:
The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
Public/Granted literature
- US20220372015A1 SUBSTITUTED PYRIMIDINES AND METHODS OF USE Public/Granted day:2022-11-24
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