- 专利标题： Benzimidazole derivative compounds and uses thereof
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申请号： US17126358申请日： 2020-12-18
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公开(公告)号： US11661419B2公开(公告)日： 2023-05-30
- 发明人: Scott William Bagley , Agustin Casimiro-Garcia , Xiayun Cheng , Jennifer Elizabeth Davoren , Rajiah Aldrin Denny , Brian Stephen Gerstenberger , Frank Eldridge Lovering , Mihir Dineshkumar Parikh , Joseph Walter Strohbach , John Isidro Trujillo
- 申请人： Pfizer Inc.
- 申请人地址： US NY New York
- 专利权人： Pfizer Inc.
- 当前专利权人： Pfizer Inc.
- 当前专利权人地址： US NY New York
- 代理商 Young-In Julia Oh
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; A61P17/00 ; A61K45/06
摘要：
The invention relates to benzimidazoles of Formula (I)
and pharmaceutically acceptable salts thereof, wherein R1 to R6 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes.
The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.
and pharmaceutically acceptable salts thereof, wherein R1 to R6 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes.
The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.
公开/授权文献
- US20210188829A1 Chemical Compounds 公开/授权日：2021-06-24
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