- 专利标题： Compounds for the treatment of acute and chronic kidney disease
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申请号： US17529201申请日： 2021-11-17
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公开(公告)号： US11623918B2公开(公告)日： 2023-04-11
- 发明人: Mark J. Suto , Bini Mathew , Anupam Agarwal , Amie M. Traylor
- 申请人： Southern Research Institute , UAB Research Foundation , The United States Government as Represented by the Department of Veterans Affairs
- 申请人地址： US AL Birmingham; US AL Birmingham; US DC Washington
- 专利权人： Southern Research Institute,UAB Research Foundation,The United States Government as Represented by the Department of Veterans Affairs
- 当前专利权人： Southern Research Institute,UAB Research Foundation,The United States Government as Represented by the Department of Veterans Affairs
- 当前专利权人地址： US AL Birmingham; US AL Birmingham; US DC Washington
- 代理机构： Ballard Spahr LLP
- 主分类号： C07D215/36
- IPC分类号： C07D215/36 ; C07D215/40 ; C07D215/48 ; C07D213/70 ; C07D217/22 ; C07C321/28
摘要：
The present disclosure is concerned with thioquinolinone compounds for the treatment of disorders associated with heme oxygenase-1 (HO-1) signaling dysfunction such as, for example, kidney diseases (e.g., chronic kidney disease, acute kidney injury). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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