Embodiments in the present disclosure relate generally to computer network architectures for machine learning, artificial intelligence, and active updates of outcomes. Embodiments of computer network architecture automatically update forecasts of outcomes of patient episodes and annual costs for each patient of interest after hospital discharge. Embodiments may generate such updated forecasts either occasionally on demand, or periodically, or as triggered by events such as an update of available data for such forecasts. Embodiments may include a combination of third-party databases to generate the updated forecasts for pending patient clinical episodes, and to drive the forecasting models for the same, including social media data, financial data, socio-economic data, medical data, search engine data, e-commerce site data, and other databases.