A medical operation system includes an information processing apparatus, including processing circuitry configured to cause a map of an operating room to be displayed on a display, the map including an icon representing a device located in the operating room or accessible from the operating room, receive, via a user operation on the displayed map, designation information representing a designation of a change in at least one of an input source, an output destination, or an internal setting for the device, generate a control signal to control the device based on the designation information, and transmit the generated control signal to the device.