Systems and methods for improved heating, ventilation, air conditioning, and refrigeration systems incorporating a plurality of refrigerant circuits. The system can include a compressor having a first compression chamber, a second compression chamber, and a motor. The system can further include a heat exchanger having a first set of microchannel coils and a second set of microchannel coils. The system can have a first circuit fluidly coupled between the first compression chamber and the first set of microchannel coils and a second circuit fluidly coupled between the second compression chamber and the second set of microchannel coils. Further, the first circuit comprises a first refrigerant and the second circuit comprises a second refrigerant.