An information system manages use of one or more areas in a vehicle permitted to be used as a pick-up and delivery destination of a pick-up and delivery product. The information system includes an information processing device. The information processing device acquires state information including at least one of information on a parking state of the vehicle and information on a surroundings situation of a parking position of the vehicle, and provides determination information for assisting in a determination as to whether or not pick-up and delivery of the pick-up and delivery product to the one or more areas is possible based on the state information, to an external device that is provided external to the information processing device.