A flexible approach to segmenting a resource (e.g., a media resource, such as a media segment, or other resource, such as a resource normally fetched or pushed using general file transfer protocols like HTTP) into a plurality of fragments. By employing such an approach, the delay until the resource can be utilized at the client side is reduced. Certain embodiments are provided which apply the flexible segmentation approach to ISOBMFF media segments for video streaming, such as would be used with Live DASH streaming.