- 专利标题： Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof
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申请号： US16919853申请日： 2020-07-02
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公开(公告)号： US11529350B2公开(公告)日： 2022-12-20
- 发明人: Adam Siddiqui-Jain , Jeyaprakashnarayanan Seenisamy , Steven L. Warner , Clifford J. Whatcott , David J. Bearss
- 申请人： Sumitomo Pharma Oncology, Inc.
- 申请人地址： US MA Cambridge
- 专利权人： Sumitomo Pharma Oncology, Inc.
- 当前专利权人： Sumitomo Pharma Oncology, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Hamilton, Brook, Smith & Reynolds, P.C.
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K31/415 ; A61K31/69 ; C07D401/14
摘要：
Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein values for the variables (e.g., X1, X2, R2, R3, R4, R5, R6, R7, R8, m, n) are as described herein. Compounds of Formula I, pharmaceutically acceptable salts thereof, pharmaceutical compositions of either of the foregoing, and combinations of any of the foregoing can be used to treat tyrosine kinase non-receptor 1 (TNK1)-mediated diseases, disorders and conditions.
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