A shield for a port closure of a medical container includes housing comprising two movably connected housing segments, each having a hollow interior and an open end, movable between open and closed orientations. A lock assembly is structured to define a fixed locked connection between the housing segments in the closed orientation and includes first and second lock members connected within different ones of the housing segments in a non-accessible location when the housing segments are in the closed orientation. A retainer is disposed within the housing in a capturing orientation relative to the closure therein, concurrent to the closed orientation. A latch assembly is connected to the housing segments and structured to retain said housing segments in said closed orientation, independently of and concurrently with the fixed locked connection of the lock assembly.