Provided are a system and method for managing a neuromorphic memory. The system includes a memory having a multi-dimensional lattice structure, a prescience estimator (PSE) configured to separately estimate memory use of two or more data sets and determine a sequence of inputting the two or more data sets to the memory, and a prescience manager (PSM) configured to allocate memory regions in which the two or more data sets will be stored according to estimation results of the PSE, store the data sets, and perform learning and inference.