Disclosed is a prefabricating and stacking combined data center. The data center is formed block structures in a multi-dimensional stacking manner. The block structures are disposed to be a fire protection layer, an air return layer, a bridge architecture wiring layer, a top-cabinet wiring layer, a cabinet device layer, and an air supply layer from up to down, which are independent from each other. Provided is a prefabricating and stacking combined data center. Operation difficulty of site construction is greatly reduced by prefabricating block structures by a factory, forming the data center by multi-dimensional stacking, and connecting the block structures with each other by splicing on site. In addition, according to different requirements of customers, corresponding ancillary facilities may be designed based on volume of an IT device, and the device and a computer room may be reasonably and effectively arranged according to the corresponding national standards and specifications.