- 专利标题： Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells
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申请号： US16613355申请日： 2017-05-15
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公开(公告)号： US11413311B2公开(公告)日： 2022-08-16
- 发明人: Ehud Marom , Nadav Bleich Kimelman , Frida Grynspan
- 申请人： STEM CELL MEDICINE LTD. , MAPI PHARMA LTD.
- 申请人地址： IL Jerusalem; IL Ness Ziona
- 专利权人： STEM CELL MEDICINE LTD.,MAPI PHARMA LTD.
- 当前专利权人： STEM CELL MEDICINE LTD.,MAPI PHARMA LTD.
- 当前专利权人地址： IL Jerusalem; IL Ness Ziona
- 代理机构： Rothwell, Figg, Ernst & Manbeck, P.C.
- 国际申请： PCT/IL2017/050535 WO 20170515
- 国际公布： WO2018/211486 WO 20181122
- 主分类号： A61K35/28
- IPC分类号： A61K35/28 ; A61P25/00 ; A61K38/02 ; A61K9/00
摘要：
Methods of treating multiple sclerosis are provided, comprising parenterally administering glatiramer acetate in a sustained-release depot form, and administering adipose-derived stem cells into the central nervous system. According to some aspects the combined treatments provide synergistic effects. In particular the combined therapies offer benefits to progressive forms of multiple sclerosis.
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