发明授权
- 专利标题: Determining potential cancer therapeutic targets by joint modeling of survival events
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申请号: US16011231申请日: 2018-06-18
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公开(公告)号: US11410745B2公开(公告)日: 2022-08-09
- 发明人: Zhaonan Sun , Zach Shahn , Ping Zhang , Fei Wang , Jianying Hu
- 申请人: International Business Machines Corporation
- 申请人地址: US NY Armonk
- 专利权人: International Business Machines Corporation
- 当前专利权人: International Business Machines Corporation
- 当前专利权人地址: US NY Armonk
- 代理机构: Amin, Turocy & Watson, LLP
- 主分类号: G16B5/00
- IPC分类号: G16B5/00 ; G16H10/60 ; G16H50/30 ; G16B10/00 ; G16B20/00
摘要:
Techniques are described that facilitate determining potential cancer gene therapy targets by joint modeling of cancer survival events. In one embodiment, a computer-implemented comprises employing, by a device operatively coupled to a processor, a multi-task learning model to determine active genetic factors respectively associated with different types of cancer based on cancer survival data and patient genomic data for groups of patients that respectively survived the different types of cancer. The computer-implemented method further comprises, determining, by the device, common active genetic factors of the active genetic factors that are shared between two or more types of cancer of the different types of cancer.
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