- 专利标题： Macrocyclic compounds and uses thereof
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申请号： US16764245申请日： 2018-11-15
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公开(公告)号： US11407762B2公开(公告)日： 2022-08-09
- 发明人: Yoshito Kishi , Kazunobu Kira , Ken Ito
- 申请人： President and Fellows of Harvard College , Eisai R&D Management Co., LTD.
- 申请人地址： US MA Cambridge; JP Tokyo
- 专利权人： President and Fellows of Harvard College,Eisai R&D Management Co., LTD.
- 当前专利权人： President and Fellows of Harvard College,Eisai R&D Management Co., LTD.
- 当前专利权人地址： US MA Cambridge; JP Tokyo
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 国际申请： PCT/US2018/061250 WO 20181115
- 国际公布： WO2019/099646 WO 20190523
- 主分类号： C07D493/22
- IPC分类号： C07D493/22 ; A61P35/04
摘要：
The present invention provides novel compounds (e.g., compounds of Formulae (I), (II), (III), (IV)) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or pharmaceutically acceptable salts thereof, optionally in a pharmaceutically acceptable carrier, and a medical uses thereof.
公开/授权文献
- US20200325152A1 MACROCYCLIC COMPOUNDS AND USES THEREOF 公开/授权日：2020-10-15
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