- 专利标题: SBE aptamers for treating IL-17a related diseases and conditions
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申请号: US16632757申请日: 2018-07-19
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公开(公告)号: US11352630B2公开(公告)日: 2022-06-07
- 发明人: Xiaoxia Li , Tomasz Herjan , Lingzi Hong , Donna Marie Driscoll , Caini Liu
- 申请人: The Cleveland Clinic Foundation
- 申请人地址: US OH Cleveland
- 专利权人: The Cleveland Clinic Foundation
- 当前专利权人: The Cleveland Clinic Foundation
- 当前专利权人地址: US OH Cleveland
- 代理机构: Casimir Jones, S.C.
- 代理商 Jason R. Bond
- 国际申请: PCT/US2018/042899 WO 20180719
- 国际公布: WO2019/018652 WO 20190124
- 主分类号: C12N15/115
- IPC分类号: C12N15/115 ; A61P37/06 ; A61K31/713
摘要:
Provided herein are compositions, systems, kits, and methods for treating IL-17a related diseases and conditions using an SBE nucleic acid sequence that binds a SEFIR domain of an ACT1 protein.
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