The invention relates to a terminal block structure includes an insulative base, a conductive terminal, a pressing element, and a clamping elastic piece. The insulative base has a chamber, a wire insertion hole and an open trough disposed on the same side of the insulative base as the wire insertion hole. The conductive terminal is fixed in the chamber and arranged correspondingly to the wire insertion hole. The pressing element includes a pivoting portion, an arm, a handle, and a pressing portion. The pivoting portion is pivotally connected to the insulative base. The arm protrudes from the insulative base through the open trough. The handle is movable beside the wire insertion hole. The clamping elastic piece is disposed in the chamber. An end of the clamping elastic piece is operatively moved to inside or outside of the wire insertion hole through the pressing portion.