Systems and methods are provided for training object detectors of a neural network model with a mixture of label noise and bounding box noise. According to some embodiments, a learning framework is provided which jointly optimizes object labels, bounding box coordinates, and model parameters by performing alternating noise correction and model training. In some embodiments, to disentangle label noise and bounding box noise, a two-step noise correction method is employed. In some examples, the first step performs class-agnostic bounding box correction by minimizing classifier discrepancy and maximizing region objectness. In some examples, the second step uses dual detection heads for label correction and class-specific bounding box refinement.