- 专利标题： Biomarkers and methods of treating PD-1 and PD-L1 related conditions
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申请号： US14850462申请日： 2015-09-10
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公开(公告)号： US11299544B2公开(公告)日： 2022-04-12
- 发明人: Daniel Shin-Yu Chen , Priti Hegde , Hartmut Koeppen , Marcin Kowanetz
- 申请人： Genentech, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Clark & Elbing LLP
- 代理商 Thomas J. Takara
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; A61K39/00 ; C07K16/28 ; C12Q1/6886 ; G01N33/68 ; G06Q30/02
摘要：
Provided herein are biomarkers for the treatment of pathological conditions, such as cancer, and method of using PD-1/PD-L1 pathway antagonists. In particular, provided are biomarkers for patient selection and prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.
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