Described techniques select portions of an audio stream for transmission to a trained machine learning application, which generates response recommendations in real-time. This real-time response is facilitated by the system identifying, selecting and transmitting those portions of the audio stream likely to be most relevant to the conversation. Portions of an audio stream less likely to be relevant to the conversation are identified accordingly and not transmitted. The system may identify the relevant portions of an audio stream by detecting events in a contemporaneous event stream, use a trained machine learning model to identify events in an audio stream, or both.