发明授权
- 专利标题： Probes for improved melt discrimination and multiplexing in nucleic acid assays
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申请号： US16804060申请日： 2020-02-28
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公开(公告)号： US11261481B2公开(公告)日： 2022-03-01
- 发明人: Doug Whitman , Nicolas Arab , Chuck Collins
- 申请人： LUMINEX CORPORATION
- 申请人地址： US TX Austin
- 专利权人： LUMINEX CORPORATION
- 当前专利权人： LUMINEX CORPORATION
- 当前专利权人地址： US TX Austin
- 代理机构： Parker Highlander PLLC
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/00 ; C12Q1/6818
摘要：
Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.
信息查询
