An interrupt signal is provided to a guest operating system executed using one or more processors of a plurality of processors. One of the processors receives from a bus attachment device an interrupt signal issued by a bus connected module. A logical processor ID resulting from a translation of an interrupt target ID provided with the interrupt signal is used to address the receiving processor directly. The receiving processor checks whether interrupt target ID identifies the receiving processor as a target processor of the interrupt signal. If the receiving processor is not the target processor, the interrupt signal is forwarded for handling by the guest operating system using broadcasting.