- 专利标题： Stabilized radio-labeled anti-CD45 immunoglobulin compositions
-
申请号： US16456614申请日： 2019-06-28
-
公开(公告)号： US11241512B2公开(公告)日： 2022-02-08
- 发明人: Kaushik Dave , Shubh Sharma
- 申请人： Actinium Pharmaceuticals, Inc.
- 申请人地址： US NY New York
- 专利权人： Actinium Pharmaceuticals, Inc.
- 当前专利权人： Actinium Pharmaceuticals, Inc.
- 当前专利权人地址： US NY New York
- 代理机构： Dentons Cohen & Grigsby P.C.
- 主分类号： A61K51/10
- IPC分类号： A61K51/10 ; A61K35/28 ; C07K16/28 ; C07K16/30 ; A61K39/395 ; A61K9/00 ; A61K47/22 ; A61K47/32 ; A61K47/42 ; A61K35/12 ; A61K39/00
摘要：
Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas.
公开/授权文献
信息查询
