- 专利标题： Methods of treating depression using orexin-2 receptor antagonists
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申请号： US17092725申请日： 2020-11-09
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公开(公告)号： US11241432B2公开(公告)日： 2022-02-08
- 发明人: Peter De Boer , Justine M. Kent , Wayne C. Drevets
- 申请人： Janssen Pharmaceutica NV
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 代理机构： BakerHostetler
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K45/06 ; A61K9/00 ; A61K9/20 ; A61K47/38 ; A61K9/10 ; A61K31/53 ; A61K31/50
摘要：
The present disclosure is directed to, inter alia, methods of treating a subject suffering from or diagnosed with depression, comprising administering to a subject in need of such treatment an effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 to R4 are described herein and wherein the compound is administered prior to sleep.
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