- 专利标题： Prodrugs of quinuclidine ring-containing muscarinic agonists and compositions and methods thereof
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申请号： US16700088申请日： 2019-12-02
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公开(公告)号： US11214569B2公开(公告)日： 2022-01-04
- 发明人: Gerald Horn
- 申请人： Lenz Therapeutics, Inc.
- 申请人地址： US CA Rancho Santa Fe
- 专利权人： Lenz Therapeutics, Inc.
- 当前专利权人： Lenz Therapeutics, Inc.
- 当前专利权人地址： US CA Rancho Santa Fe
- 代理机构： Wood, Phillips, Katz, Clark & Mortimer
- 主分类号： C07D453/02
- IPC分类号： C07D453/02 ; C07F9/59 ; C07F9/6561 ; C07D453/00 ; A61P27/06 ; A61K47/40
摘要：
The present invention is directed to compounds of the formula and salts or esters thereof. The present invention is further directed to ophthalmological compositions comprising a therapeutically effective amount of a compound of the present invention and one or more pharmaceutically acceptable excipients. The present invention is further directed to a methods of treating presbyopia or glaucoma or reducing hyperemia comprising administering to a patient in need thereof a therapeutically effective amount of a compound of the present invention.
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