- 专利标题： Compositions and methods for regulating erythropoiesis
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申请号： US16139428申请日： 2018-09-24
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公开(公告)号： US11117976B2公开(公告)日： 2021-09-14
- 发明人: Thomas J. Braciale , Taeg S. Kim
- 申请人： University of Virginia Patent Foundation
- 申请人地址： US VA Charlottesville
- 专利权人： University of Virginia Patent Foundation
- 当前专利权人： University of Virginia Patent Foundation
- 当前专利权人地址： US VA Charlottesville
- 代理机构： Jenkins, Wilson, Taylor & Hunt, P.A.
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/18 ; A61K38/19 ; A61K38/20 ; C07K16/28 ; A61K39/395 ; A61K45/06 ; A61K38/00
摘要：
The present application discloses a previously unknown function of CD24 expressed on a subset of dendritic cells. The invention encompasses regulating CD24 on these cells to regulate erythropoiesis, induce EPO production and levels, increase RBC levels, and to treat, for example, stress-mediated erythropoiesis. The compositions and methods of the invention are useful, for example, in treating anemia.
公开/授权文献
- US20190071515A1 COMPOSITIONS AND METHODS FOR REGULATING ERYTHROPOIESIS 公开/授权日：2019-03-07
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