- 专利标题： Peptide macrocycles against Acinetobacter baumannii
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申请号： US16006564申请日： 2018-06-12
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公开(公告)号： US11098080B2公开(公告)日： 2021-08-24
- 发明人: Alexander Alanine , Julien Beignet , Konrad Bleicher , Bernhard Fasching , Hans Hilpert , Taishan Hu , Dwight MacDonald , Stephen Jackson , Sabine Kolczewski , Carsten Kroll , Adrian Schaeublin , Hong Shen , Theodor Stoll , Helmut Thomas , Amal Wahhab , Claudia Zampaloni
- 申请人： Hoffmann-La Roche Inc.
- 申请人地址： US NJ Little Falls
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Little Falls
- 代理商 Andre T. Krammer
- 优先权： EP15191743 20151027
- 主分类号： C07K5/08
- IPC分类号： C07K5/08 ; C07K5/02 ; C07K5/068 ; C07K5/083 ; C07K5/087 ; C07K5/09 ; C07K5/097 ; A61K38/00
摘要：
The present invention provides compounds of formula (I) wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.
公开/授权文献
- US20180362578A1 PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII 公开/授权日：2018-12-20
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