An integrated sensor assembly provides multiple sensing modalities to monitor an agricultural environment, and may be employed in or used with controlled environment agriculture (CEA) systems to control and maintain improved growth conditions for various plants. In one exemplary implementation, an integrated sensor assembly includes sensors to monitor parameters important to plant growth, such as a natural light sensor, an air temperature sensor, a relative humidity sensor, an air flow sensor, a carbon dioxide (CO2) sensor, and a remote infrared (IR) temperature sensor. The sensors are mounted onto a single circuit board, which is then placed inside a housing for protection from the ambient environment. The housing can include one or more openings and apertures to facilitate sensing with protective covers where appropriate. A USB port can be included to supply electrical power and transfer of data to and from the integrated sensor assembly (e.g., to provide plug-and-play functionality).