- 专利标题: Systems, apparatus and methods for sealing perivalvular leaks
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申请号: US15835714申请日: 2017-12-08
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公开(公告)号: US10993802B2公开(公告)日: 2021-05-04
- 发明人: Robert G Matheny
- 申请人: CorMatrix Cardiovascular, Inc.
- 申请人地址: US GA Roswell
- 专利权人: CorMatrix Cardiovascular, Inc.
- 当前专利权人: CorMatrix Cardiovascular, Inc.
- 当前专利权人地址: US GA Roswell
- 代理机构: Francis Law Group
- 主分类号: A61F2/24
- IPC分类号: A61F2/24
摘要:
A biocompatible and biodegradable construct having a base expandable member and an integral, internal support structure. The support structure is preferably formed from poly(glycerol sebacate) (PGS) or a magnesium alloy. The base member is preferably formed from acellular extracellular matrix (ECM) derived from small intestine submucosa (SIS) tissue that exhibits a flexible, porous, sponge-like structure adapted to expand upon absorption of a bodily fluid, wherein the construct seals a perivalvular leak when disposed proximate thereto.
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